Temperature-humidity synergistic effects on predominant intestinal infectious diseases in Shenzhen, China: A predictive modeling framework for epidemiological early warning systems.

ABSTRACT: The prevalence of intestinal infectious diseases (IIDs) in densely populated cities substantially escalates the burden of disease. An ecological study on the epidemiological trends of predominant IIDs-hand, foot, and mouth disease (HFMD), viral diarrhea (DV), and non-viral diarrhea (DN)-was conducted in Shenzhen, China (2012-2022), aiming to elucidate the associations of meteorological factors, including extreme temperatures, seasonal variations, and temperature-humidity interactions with IID transmission, and to establish a monitoring and early warning framework. We assessed temperature-related morbidity's short-term lagged effects, long-term cumulative impacts, and seasonal patterns using distributed lag non-linear models, finding that high temperatures (30°C) significantly increase HFMD

SUBMITTER: Lyu H 

PROVIDER: S-EPMC12680148 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature