Sense-checking the approach to quantitative sensory testing to detect chemotherapy-induced peripheral neuropathy.

ABSTRACT: People with chemotherapy-induced peripheral neuropathy (CIPN) have abnormalities in Quantitative Sensory Test (QST) findings. However, the predictive utility of QST for the early detection of CIPN in individuals has not been demonstrated. This will require longitudinal QST during chemotherapy treatments. However, QST is time-consuming, requires expertise and complex, costly equipment which has largely prevented its adoption in routine clinical practice. We aimed to assess approaches to develop a reliable, straightforward, time efficient and sensitive sensory testing method. Guided by patient partner input and previous literature, we selected thermal and vibration detection thresholds as target QST parameters. A series of iterative experiments was conducted to determine the optimal body tes

SUBMITTER: Dujmovic M 

PROVIDER: S-EPMC12680151 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature