Neisseria meningitidis serogroup B causing invasive disease, Italy, 2010-2021.

ABSTRACT: In Italy, Invasive Meningococcal Disease (IMD) due to Neisseria meningitidis serogroup B (MenB) showed the highest incidence rates in infants under one year of age. This study describes the main characteristics of MenB responsible for invasive diseases circulating in Italy from 2010 to 2021. Data collected within the framework of National Surveillance System (NSS) for IMD were analysed. Serogroup confirmed IMD cases were included in the study. For unspecified meningococcal serogroup, a multinomial model was used to impute the serogroup. Antimicrobial susceptibility and genotyping by Sanger or whole genome sequencing were performed on viable meningococci. Core genome MLST (cgMLST) was evaluated using a gene-by-gene approach, and MenDeVAR analyses were used to assess potential coverage by Me

SUBMITTER: Vacca P 

PROVIDER: S-EPMC12680181 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature