Acupuncture (Jin's Three-Needle) versus sham acupuncture in treating mild-to-moderate depression: Study protocol for randomized clinical trial.

ABSTRACT:

Background

Mild-to-moderate depression is an increasing public health problem worldwide, which is more prevalent than major depression but has received less attention Currently, no existing highly effective pharmacological treatments with minimal adverse reactions are available for this condition. Jin's Three-Needle Acupuncture (JTN) may be an alternative treatment option for mild-to-moderate depression patients.

Methods

This is a prospective, parallel-arm, single-blind, randomized controlled trial. We plan to enroll 106 participants with mild-to-moderate depression, randomly assigning them to receive either JTN or sham acupuncture (SA) in a 1:1 ratio. All participants will receive the JTN treatment or SA treatment for 8 weeks (3 per week). The primary outcome will be assess

SUBMITTER: Wen H 

PROVIDER: S-EPMC12680233 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature