Complications and oncologic outcome in bladder cancer patients receiving radical cystectomy after intravesical instillation treatment.

ABSTRACT:

Objective

To evaluate the impact of previous intravesical treatment with Bacillus Calmette-Guérin (BCG) or mitomycin on postoperative complications and oncologic outcome in non-muscle invasive bladder cancer (NMIBC) patients receiving radical cystectomy (RC).

Patients and methods

Between 2016 and 2021, 366 patients who received RC for bladder cancer (BC) were screened. Patients with intravesical treatment with either BCG or mitomycin for NMIBC were compared to patients with BC without prior intravesical treatment. Patients were matched manually for ASA-score, BMI cluster, age, and sex. TNM stages were used as covariates in the analysis model. All complications within 30 days post-surgery and the 90-day mortality rates were analyzed. Patient characteristics were compared betw

SUBMITTER: Frey LJ 

PROVIDER: S-EPMC12680265 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature