The association between a newly proposed gut microbiota dietary index and obesity among U.S. adults: a cross-sectional analysis based on NHANES 1999-2020.

ABSTRACT:

Objective

Obesity is linked to gut microbiota dysbiosis, and diet is a key determinant influencing the gut microbiome. This study examined the association between a newly proposed Dietary Index for Gut Microbiota (DI-GM) and obesity in the National Health and Nutrition Examination Survey (NHANES) from 1999 to 2020.

Methods

A total of 41,159 adults aged ≥ 20 years were included, with 15,327 individuals classified as obese (BMI ≥ 30 kg/m²) and 25,832 as living without obesity. DI-GM comprises 13 components deemed either beneficial or unfavorable to the gut microbiome, yielding a total score ranging from 0 to 13. Weighted logistic regression assessed the relationship between DI-GM (continuous and categorical) and obesity, adjusting for demographic and lifestyle factors plus com

SUBMITTER: Huang Y 

PROVIDER: S-EPMC12681089 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature