The impact of early-life rearing conditions on the porcine gut microbiota and immune system.

ABSTRACT:

Background

Early life represents an unparalleled window in the life of the pig in which the gut microbiota interacts with its host's naïve immune system. Yet, modern swine production often favours conditions that promote production efficiency rather than enriched microbiota development, the long-term consequences of which remain poorly understood. This study sought to analyse the long-term impacts of early-life rearing conditions on the gut microbiota until day 90, and in turn, its physiological and immunological consequences. We established two rearing conditions from farrowing until day 90: enriched, microbiota-enhancing husbandry characterised by weaning at 6 weeks and the provision of litter material throughout; and restricted, microbiota-depleting husbandry comprising weaning

SUBMITTER: Comer L 

PROVIDER: S-EPMC12681121 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature