Combined angiography and perfusion using radial imaging and arterial spin labeling with structural contrast.

ABSTRACT:

Purpose

To develop a non-contrast MRI method for the simultaneous acquisition of time-resolved 3D angiographic, perfusion, and multi-contrast T₁-weighted structural brain images in a single 6 min acquisition.

Methods

The proposed combined angiography and perfusion using radial imaging and arterial spin labeling with structural contrast (CAPRIA+S) pulse sequence uses pseudocontinuous arterial spin labeling to label inflowing blood, an inversion pulse to provide background suppression and T₁-weighted contrast, and a continuous 3D golden ratio spoiled gradient echo readout. Label-control subtraction isolates the blood signal which can be flexibly reconstructed at high/low spatiotemporal resolution for angiography/perfusion imaging. The mean signal retains

SUBMITTER: Okell TW 

PROVIDER: S-EPMC12681295 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature