The relationship between blood pressure and cognitive decline differs by race.

ABSTRACT:

Background and objectives

Cognition may be influenced by health-related factors such as blood pressure (BP). However, variations in BP may differentially affect cognition across race. This study investigates BP and cognitive decline in older Black and White adults.

Research design and methods

A total of 2,284 participants (1,139 Blacks, 1,145 Whites, MAge = 73.4) from three harmonized cohorts of older adults from the Rush Alzheimer's Disease Center, were divided into three groups (normal, high, variable) based on systolic BP mean and standard deviation. Cognitive scores were computed from 18 neuropsychological tests and averaged to summarize five domains (episodic memory, semantic memory, working memory, processing speed, visuospatial ability) and a measure of global cogniti

SUBMITTER: Oliver MD 

PROVIDER: S-EPMC12681357 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature