Physical fitness, cognition, and structural network efficiency of brain connections across the lifespan.

ABSTRACT: Inadequate levels of exercise is one of the most potent modifiable risk factors for preventing cognitive decline and dementia as we age. Meanwhile, network science-based measures of structural brain network global and local efficiency show promise as robust biomarkers of aging, cognitive decline, and pathological disease progression. Despite this, little to no work has established how maintaining physical activity (PA) and physical fitness might relate to cognition and network efficiency measures across the lifespan. Therefore the purpose of this study was to determine the relationship between (1) PA and fitness and cognition, (2) fitness and network efficiency, and (3) how network efficiency measures relate to cognition. To accomplish this, we analyzed a large cross-sectional data set (n 

SUBMITTER: Callow DD 

PROVIDER: S-EPMC12681381 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature