Nationwide trends and disparities in deaths from second- or third-degree atrioventricular block (1999-2022): A 24-year retrospective analysis of CDC WONDER data.

ABSTRACT:

Background

AV block prevalence increases with age: first-degree affects 6 % of adults over 60 with low mortality, second-degree is more serious, and third-degree, though rare (0.02 % in the U.S.), has a 37 % five-year survival rate if untreated. Analyzing mortality trends in second- or third-degree AV blocks in the U.S. is vital for treatment and identifying at-risk populations.

Methodology

We analyzed death certificates from the CDC WONDER database (1999-2022) for second- and third-degree AV Block (ICD-10 codes I44.1 and I44.2) in individuals aged 25 and older. Age-adjusted mortality rates (AAMRs) and annual percent change (APC) were calculated by year, sex, age, race/ethnicity and geographics.

Results

Between 1999 and 2022, 54,420 deaths were reported in patients wi

SUBMITTER: Saeed H 

PROVIDER: S-EPMC12681512 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature