Comparing various frailty instruments for predicting adverse outcomes in older patients hospitalized with lower respiratory tract infections.

ABSTRACT:

Objective

Frailty is increasingly recognized in older adults with lower respiratory tract infections (LRTIs), yet the optimal assessment tool and its prognostic value remain unclear. This study evaluates the prevalence, inter-tool agreement, and predictive performance of four frailty measures in this population.

Methods

Older adults hospitalized with LRTIs were prospectively enrolled. Frailty was assessed using the Clinical Frailty Scale (CFS), Fried Frailty Phenotype (FFP), FRAIL Scale (FS), and Short Physical Performance Battery (SPPB). The primary outcome was 1-year mortality; secondary outcomes included in-hospital mortality and decline in activities of daily living (ADL) at discharge and 1 year. Inter-tool agreement was assessed using Cohen's kappa, and predictive perfo

SUBMITTER: Weng B 

PROVIDER: S-EPMC12681707 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature