Economic evaluation of potential national childhood screening strategies for type 1 diabetes in Australia.

ABSTRACT:

Background

Type 1 diabetes (T1D) is an autoimmune condition affecting children. We aimed to investigate the costs and cost-effectiveness of potential national childhood screening strategies for T1D compared to no screening (usual care).

Methods

Screening costs were obtained from trial-based estimates. A Markov microsimulation model was developed to identify the most cost-effective childhood T1D screening strategy. The three screening strategies modelled were: Strategy 1) newborn genetic risk-stratification with bloodspot sampling, followed by autoantibody screening in at-risk children; Strategy 2) infant genetic risk-stratification using saliva sampling, followed by autoantibody screening in at-risk children; Strategy 3) population-wide autoantibody screening at two childhoo

SUBMITTER: Chen W 

PROVIDER: S-EPMC12681985 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature