Computational fluid dynamics modeling and simulation of nanoparticle-tumor interaction: Systematic literature review.

ABSTRACT: Cancer therapy mediated by nanoparticles is gaining recognition for shifting the paradigm of targeted and/or personalized cancer therapy. Despite the great promise, only a few nanoformulations have been clinically approved due to the complexities that limit effective and efficient nanodrug development. Moreover, the preparation of cancer nanodrug has not yet been optimized for clinical approval in patient treatment. Computational fluid dynamics (CFD) is a new technique that simulates and analyzes fluid flows and their interactions with surfaces using computer algorithms and numerical analysis. This simulation and modeling tool provides a distinct advantage in understanding tumor-host mechano-biology and mechanisms that help identify the main factors affecting the transport of tumor-targeti

SUBMITTER: Mmereke KM 

PROVIDER: S-EPMC12682063 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature