Integrated analysis of time- and concentration-dependent metabolomics unravel metabolic changes in raw beef preserved using bacteriocin XJS01.

ABSTRACT: This study determined the preservation effects of bacteriocin XJS01 on raw beef during storage at 4 °C. An integrated time- and concentration-dependent metabolomic analysis revealed that XJS01 preserved beef by influencing metabolic pathways of spoilage-induced bacteria. These pathways were primarily associated with meat spoilage, cell structure and stress response. The results also demonstrated that the antibacterial activity of XJS01 contributed to preservation by indirectly suppressing the formation of dipeptides. Additionally, 37 metabolites were significantly correlated with meat-quality traits, which were primarily related to valine, leucine and isoleucine degradation and alpha-linolenic acid metabolism. Meanwhile, 1,2,10-trihydroxydihydro-trans-linalyl oxide7-O-beta-D-glucopyranosid

SUBMITTER: Ying JP 

PROVIDER: S-EPMC12682151 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature