Depression preceding and following the diagnosis of Parkinson's disease and Lewy body dementia.

ABSTRACT:

Background

Depression is a common comorbidity in Parkinson's disease (PD) and Lewy body dementia (LBD). However, studies examining the rate of incident depression in the period preceding and following the diagnosis of PD and LBD are lacking in the literature.

Aims

To quantify the incidence of depression in the period preceding and following the diagnosis of PD and LBD.

Methods

We conducted a retrospective case-control study. Specifically, we used Danish registers to identify all patients with a diagnosis of PD or LBD in the period from 2007 to 2019. These patients were matched by age, calendar year of diagnosis and sex with up to three patients diagnosed with rheumatoid arthritis (RA), chronic kidney disease (CKD) or osteoporosis, respectively. The outcome was inciden

SUBMITTER: Rohde C 

PROVIDER: S-EPMC12682179 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature