CMR-based left atrial strain for predicting left ventricular diastolic dysfunction in asymptomatic hypertensive patients.

ABSTRACT:

Background

Left ventricular diastolic dysfunction (LVDD) is highly prevalent in hypertension (HTN) and is strongly associated with heart failure with preserved ejection fraction (HFpEF). However, conventional cardiac magnetic resonance (CMR) protocols lack guideline-recommended hemodynamic parameters for diastolic function assessment, thereby limiting their utility in LVDD evaluation. This study employed CMR feature tracking (CMR-FT) to analyze left atrial (LA) function in patients with subclinical HTN. We aimed to validate CMR-FT-derived LA strain as a marker for detecting LVDD with elevated left atrial pressure (LAP), thereby providing CMR parameters for diastolic dysfunction evaluation without additional scanning.

Methods

This retrospective study included 152 HTN patients

SUBMITTER: Liao W 

PROVIDER: S-EPMC12682465 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature