Dual-energy CT for distinguishing between T3 and T4 stages of locally advanced nasopharyngeal carcinoma.

ABSTRACT:

Background

T staging is closely linked to the prognosis of patients with nasopharyngeal carcinoma (NPC), and dual-energy computed tomography (DECT) has a lot of promise for determining the degree of tumor invasion in head and neck cancers. This study aims to evaluate the value of quantitative parameters of DECT in distinguishing between T3 and T4 stages of locally advanced nasopharyngeal carcinoma (LA-NPC) and to compare the diagnostic performance of DECT and magnetic resonance imaging (MRI).

Methods

This prospective study enrolled 136 patients with histologically confirmed LA-NPC. This cohort was divided into T3 and T4 stage, and the performance of DECT for staging was compared to that of MRI. Subsequently, logistic regression analysis was performed on the quantitative para

SUBMITTER: Li L 

PROVIDER: S-EPMC12682483 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature