Pulmonary arterial diameter remains dilated despite a reduction of pulmonary arterial pressure post lung transplantation: a retrospective study.

ABSTRACT:

Background

Pulmonary artery (PA) dilatation is a common feature of pulmonary hypertension (PH). While lung transplantation (LTx) leads to significant hemodynamic improvements, the effect on PA diameter remains unclear. This study aims to evaluate changes in PA diameter following LTx in patients with preexisting PH and determine whether structural vascular changes regress alongside pulmonary pressure normalization.

Methods

We retrospectively assessed 18 patients with PH who underwent LTx between 2002 and 2023. Main PA, right PA (RPA), and left PA (LPA) diameters were measured via computed tomography (CT) imaging pre-transplant and annually post-transplant (up to 12 years). Systolic pulmonary arterial pressure (SPAP) was assessed by echocardiography.

Results

Despite a s

SUBMITTER: Herzberg G 

PROVIDER: S-EPMC12682508 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature