The differentiation between primary aldosteronism and essential hypertension in left ventricular remodeling before and after treatment: a follow-up study with quantitative stress cardiac magnetic resonance imaging.

ABSTRACT:

Background

Primary aldosteronism (PA) is associated with adverse cardiovascular outcomes. Elevated aldosterone levels in PA contribute to cardiac remodeling. This study aimed to apply cardiac magnetic resonance imaging (MRI) to longitudinally compare cardiac remodeling changes before and after targeted therapy between patients with PA and those with essential hypertension (EH) and to identify independent clinical predictors of left ventricular remodeling.

Methods

We studied 75 consecutive patients with PA and 75 with EH. Patients with PA were treated with surgery, while patients with EH received pharmacotherapy. Clinical characteristics and MRI findings were collected at baseline and 6 months after treatment. Generalized estimating equations were applied to compare the chang

SUBMITTER: Tang L 

PROVIDER: S-EPMC12682559 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature