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Methodological panorama of clinical trials for diabetic foot ulcers: a scope review of design, implementation and reporting.


ABSTRACT:

Background

Diabetic foot ulcer (DFU) reduce the quality of life for diabetes patients and creates a significant economic burden on global healthcare systems. Although there has been recent progress in DFU clinical trials, most existing scoping reviews have primarily focused on nursing or diagnostic methods. This review analyzed the characteristics of current DFU clinical trials and assessed research methods. This review focused on refining trial design and provide evidence-based methods for improving treatment outcomes and prognosis.

Method

The study searched clinical trials registered in ClinicalTrials and Chinese Clinical Trial Registry (ChiCTR) (up to August 1, 2025). In addition, the study searched PubMed for clinical trials that were published from August 1, 2015, to Au

SUBMITTER: Zhang S 

PROVIDER: S-EPMC12682631 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature