Hashimoto's thyroiditis reduces central lymph node metastasis risk in papillary thyroid microcarcinoma: an integrated meta-analysis.

ABSTRACT:

Background

Hashimoto's thyroiditis (HT) is the most common comorbidity in patients with papillary thyroid microcarcinoma (PTMC). The necessity of prophylactic central lymph node dissection (CLND) in clinically node-negative (cN0) PTMC cases remains a topic of debate. This study evaluates the risk of cervical lymph node metastasis (LNM) in PTMC patients with concurrent HT.

Objectives

This study aims to evaluate the risk of central lymph node metastasis (CLNM) in patients with PTMC concurrent with HT. By synthesizing existing literature and conducting a case-control analysis, we seek to enhance individualized risk assessment and inform surgical decision-making for PTMC patients.

Methods

We conducted a search for studies published before 1 June 2025 that assessed the ris

SUBMITTER: Zhong L 

PROVIDER: S-EPMC12682656 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature