Effects of 5-Year Exercise Training on Cognition in Older Adults: 10-Years Follow-Up from the Generation 100 Study.

ABSTRACT:

Background and aim

The rapid aging of the global population is expected to lead to an increase in the incidence and prevalence of neurodegenerative diseases. Endurance exercise training is considered one of the most effective forms of prevention against neurodegenerative diseases. This study investigated the effects of a 5-year exercise training intervention at varying intensities on cognitive function in healthy older adults.

Methods

1486 healthy older men (n = 735) and women (n = 751) aged 70-77 years from Trondheim, Norway, were randomly assigned to high-intensity interval training (HIIT, n = 382), moderate-intensity continuous training (MICT, n = 367), or a control group (n = 737) following the national physical activity (PA) guidelines. Cognitive function was assessed u

SUBMITTER: Bakken J 

PROVIDER: S-EPMC12682729 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature