Enhanced bioproduction of phenolic compounds from <i>Populus nigra</i> L. using temporary immersion bioreactors and metabolomics.

ABSTRACT: Black poplar is a woody species rich in bioactive phenolic compounds with promising pharmaceutical and cosmetic applications. In wild populations, genetic diversity and environmental variability affect phenolic content and bioactivities. Plant tissue culture, conducted under controlled conditions, offers a suitable alternative for industrial bioproduction. The aim of this study was the development of in vitro shoot cultures of black poplar in Magenta™ and RITA® systems for efficient and constant phenolic productivity. Following the initiation of in vitro lines, significant growth enhancement was achieved through selection of fast-growing lines. UPLC-QTOF-MS-based untargeted metabolomic analyses were carried out, and allowed the identification of flavan-3-ols, proanthocyanidin

SUBMITTER: Laffon M 

PROVIDER: S-EPMC12682903 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature