Dietary Spirulina platensis enhances immune responses and modulates gut microbiota and microbial function in laying hens.

ABSTRACT: Growing restrictions on antibiotic use in poultry nutrition have heightened the need for natural feed additives that promote health and performance. Spirulina platensis (SP) has gained attention for its immunomodulatory and gut health benefits. This study evaluated the effects of SP supplementation on immune responses, gut microbiota composition, and microbial functional potential in White Leghorn laying hens. A total of 192 White Leghorn laying hens (39 weeks old) were randomly assigned to four dietary groups: Control (0g SP/kg feed), T1 (2.5g SP/kg feed), T2 (5g SP/kg feed), and T3 (10g SP/kg feed). Each group received its respective diet for a six-weeks duration. Serum biomarkers, including cytokines, chemokines, and growth factors, were analyzed, and microbial profiling was performed u

SUBMITTER: Salahuddin M 

PROVIDER: S-EPMC12683123 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature