Employing Triphenylene-Based, Layered, Conductive Metal-Organic Framework Materials as Electrochemical Sensors for Nitric Oxide in Aqueous Media.

ABSTRACT: This paper describes the first use of conductive metal-organic frameworks as the active material in the electrochemical detection of nitric oxide in aqueous solution. Four hexahydroxytriphenylene (HHTP)-based MOFs linked with first-row transition metal nodes (M = Co, Ni, Cu, Zn) were compared as thin-film working electrodes for promoting oxidation of NO using voltammetric and amperometric techniques. Cu- and Ni-linked MOF analogs provided signal enhancement of 5- to 7-fold over a control glassy carbon electrode (SA_NO = 6.7 ± 1.2 and 5.7 ± 1.1 for Ni₃(HHTP)₂ and Cu₃(HHTP)₂, respectively) for detecting micromolar concentrations of NO. Zinc-based MOF electrodes offered more limited enhancement (SA_NO = 3.1 ± 0.5), while the coba

SUBMITTER: Ambrogi EK 

PROVIDER: S-EPMC12683353 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature