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Effectiveness of surfactant treatment and retreatment in moderately preterm infants.


ABSTRACT:

Background

Respiratory distress syndrome (RDS) is commonly treated in preterm infants with surfactant and artificial respiratory support. However, their effects have been demonstrated in infants born before 30 weeks of gestational age, while there are no data on the efficacy of surfactant treatment and retreatment in the subgroup of moderately preterm infants (MPIs). We aimed to assess changes in oxygenation indices and RDS severity after surfactant administration in MPIs and to identify possible risk factors for the need for multiple doses of surfactant in these patients.

Methods

We conducted a retrospective study on 60 MPIs born between 30+0 and 33+6 weeks of gestational age who were affected by RDS and required surfactant treatment. Peripheral oxygen

SUBMITTER: Dani C 

PROVIDER: S-EPMC12683493 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature