Metabolic reprogramming in PGPR reveals cross-feeding-driven physiological shifts and metabolic adaptations.

ABSTRACT:

Introduction

Microbial interactions in the rhizosphere are fundamental to soil health, plant growth, and ecosystem stability. Among these interactions, metabolic cross-feeding, the exchange of metabolites between microorganisms, plays a critical role in shaping microbial community structure and function. This study investigates the metabolic interplay between two PGPR (Priestia megaterium and Bacillus licheniformis), focusing on how metabolite exchange influences bacterial growth and metabolic reprogramming.

Methods

An integrative metabolomics approach was employed to examine metabolic exchanges between P. megaterium and B. licheniformis. Cultures were grown individually and in co-culture, followed by extraction of extracellular metabolites at distinct g

SUBMITTER: Mmotla K 

PROVIDER: S-EPMC12683585 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature