Triglyceride-Glucose Body Mass Index Predicts Asthma Exacerbations: A Prospective Study.

ABSTRACT:

Purpose

Insulin resistance, a central feature of metabolic syndrome, has been associated with asthma exacerbations. However, the role of metabolic markers, specifically the triglyceride-glucose body mass index (TyG-BMI), in predicting asthma exacerbations is not fully explored. This study explored the predictive value of the TyG-BMI, a biomarker of metabolic syndrome and insulin resistance, in the risk of asthma exacerbations.

Methods

This single-center prospective cohort study enrolled 484 patients with stable asthma between March and October of 2023. The study employed K-means clustering analysis to categorize patients according to TyG-BMI. The primary endpoint was the first occurrence of asthma exacerbation during one year of follow-up. Additionally, weighted quantile sum

SUBMITTER: Gao F 

PROVIDER: S-EPMC12683744 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature