Non-mydriatic handheld optical coherence tomography for panretinal imaging.

ABSTRACT: We present a handheld, non-mydriatic optical coherence tomography (OCT) system engineered for panretinal imaging across both pediatric and adult patients. The prototype achieves a 140° visual angle, enabling detailed visualization from the posterior pole to the peripheral retina without the need for pharmacologic dilation or scleral depression. A customized optical design minimizes beam wander while maintaining diffraction-limited resolution throughout the field of view. The system employs a 400 kHz VCSEL light source, facilitating high-speed image acquisition along with an extended axial imaging range of 12 mm in air, sufficient to accommodate retinal curvature. This combination of optical and hardware enhancements allows for rapid and comprehensive retinal assessment in a variety of clin

SUBMITTER: Ni S 

PROVIDER: S-EPMC12684009 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature