Valvular Heart Disease and Its Association With Death in Advanced Heart Failure.

ABSTRACT:

Background

Valvular heart disease contributes to symptomatic heart failure, but its prevalence and prognostic significance in advanced heart failure is not well understood.

Methods

This retrospective population-based cohort study included adult residents of Olmsted County, Minnesota, with advanced heart failure (2007-2018). Patients were classified by echocardiographic regurgitation and stenosis of aortic, mitral, tricuspid, and pulmonic valves at the time of advanced heart failure. We examined the associations of aortic stenosis, mitral regurgitation, and tricuspid regurgitation with risks of cardiovascular and all-cause death through 2023 using Cox proportional hazards models.

Results

There were 936 patients with advanced heart failure (mean age, 76.9 years; 44.5% w

SUBMITTER: Steiger KG 

PROVIDER: S-EPMC12684481 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature