Individual and County-Level Social Determinants of Health and Acute Reperfusion Therapies: Get With The Guidelines-Stroke Registry Results.

ABSTRACT:

Background

The associations between individual- and county-level social determinants of health and reperfusion therapies (thrombolysis or thrombectomy) for acute ischemic stroke have been described separately, but they are rarely studied together.

Methods and results

We identified 1.5 million patients aged ≥40 years with acute ischemic stroke between January 1, 2015 and December 31, 2019 from the Get With The Guidelines-Stroke registry in the United States. We ascertained age, sex, rural residence, and ethnicity or race at the individual level, and poverty, unemployment, and lower education (defined as less than high school) at the county level. We used multivariable log-binomial regression models estimated using generalized estimating equations methods to account for county

SUBMITTER: Vyas MV 

PROVIDER: S-EPMC12684525 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature