Carotid Plaques Show More Unstable Characteristics Between 2010 and 2021 After a Prior Decade of Stabilization.

ABSTRACT:

Background

Previously we reported a time-dependent change in atherosclerotic carotid plaque characteristics, with decreasing destabilizing characteristics between 2002 and 2011. This observation was considered confirmative with a parallel improved adherence to medication and decrease in overall cardiovascular death in Western Europe. In the present study, we investigated whether these time-dependent changes in plaque characteristics still occurred over the past decade.

Methods

Using the Athero-Express biobank, atherosclerotic plaques of 1277 consecutive patients undergoing carotid endarterectomy included between 2010 and 2021 were analyzed to examine time-dependent changes in histological plaque characteristics in intervals of 2 years. These results were compared with our pr

SUBMITTER: Mol BM 

PROVIDER: S-EPMC12684537 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature