Association of Pancreas Volume With Adverse Clinical Outcomes.

ABSTRACT:

Background

Chronic diseases may injure the pancreas and result in a reduction in pancreas volume (PV), which may adversely impact its critical role in endocrine and exocrine function. Less is known about whether individuals with smaller PV face higher risks of adverse clinical outcomes.

Methods

We estimated baseline age-adjusted predicted PV (pPV) from abdominal magnetic resonance imaging in 36 592 UK Biobank participants. Since the initial magnetic resonance imaging occurred 9.0 (interquartile range, 7.5-10.1) years after baseline, we fit a linear regression equation that included age for the outcome of PV slope in 451 participants with repeat magnetic resonance imaging 2.8 (interquartile range, 2.2-4.8) years after the initial scan. Using these data, we calculated baseline

SUBMITTER: Thomas P 

PROVIDER: S-EPMC12684549 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature