Prior Dual Antiplatelet Therapy and Mortality After Intracerebral Hemorrhage: A Danish Nationwide Cohort Study.

ABSTRACT:

Background

Limited data support the link between dual antiplatelet therapy (DAPT) and adverse outcome among patients with intracerebral hemorrhage. This study aimed to investigate the association between prior use of DAPT and mortality after intracerebral hemorrhage.

Methods

Patients with first-ever intracerebral hemorrhage on current APT at the time of admission, were identified and followed 180 days after admission through the Danish nationwide registries. Prior exposure to DAPT or single APT (SAPT) was established through the Danish National Prescription Registry. Inverse probability of treatment weighting was used to control for confounding.

Results

A total of 5800 patients were on antiplatelet therapy. 5535 (95.4%) were on SAPT, and 265 (4.6%) were on DAPT. Compa

SUBMITTER: Ovesen C 

PROVIDER: S-EPMC12684552 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature