Blood Pressure Postural Changes Variability Is Associated With Lower Cognition: The S.AGES Cohort.

ABSTRACT:

Background

Over the past decade, higher blood pressure (BP) variability and postural changes in BP have been associated with lower cognitive function. However, only one study has investigated the specific association between BP postural changes variability and brain health, showing a greater risk of dementia with higher systolic BP (SBP) postural changes variability. We aimed to investigate the association between BP postural changes variability and cognitive function in community-dwelling older adults.

Methods

Participants from the S.AGES (Sujets ÂGES) cohort underwent clinical examinations every 6 months during 3 years. At each clinical visit, an orthostatic SBP ratio was calculated: (seated SBP/standing SBP)×100. A similar method was used to compute an orthostatic diastol

SUBMITTER: Strumia M 

PROVIDER: S-EPMC12684571 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature