Timing and Mode of Death Following Treatment of Neonatal Symptomatic Tetralogy of Fallot.

ABSTRACT:

Background

Neonates with tetralogy of Fallot and symptomatic cyanosis (sTOF) require early intervention, using a staged or primary repair strategy. Postprocedural mortality risk within this group is considerable. The mode of death and associated factors have been inadequately defined in early childhood mortality following treatment of sTOF. This study aims to describe the timing, cause, and associated risk factors of postprocedural death in infants with sTOF.

Methods

Neonates with sTOF who had an initial intervention from 2005 to 2017 at 9 centers of the Congenital Cardiac Research Collaborative were reviewed. Among nonsurvivors, details regarding timing, cause of death, and last follow-up were obtained. Patient characteristics between survivors and nonsurvivors were compare

SUBMITTER: Trucco SM 

PROVIDER: S-EPMC12684597 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature