Metabolic Syndrome and Risk of Moyamoya Vasculopathy and Subsequent Stroke in Young Adults.

ABSTRACT:

Background

Moyamoya vasculopathy (MMV) is a rare cerebrovascular disease of unclear cause. In this study, we aimed to determine whether metabolic syndrome (MetS) is associated with the development of MMV and subsequent stroke risk in young adults.

Methods

Using a nationwide database, we retrospectively analyzed the data of 6 891 400 Korean adults aged 20 to 40 years who underwent health screening between 2009 and 2012. Participants were monitored until December 31, 2021, to identify patients newly diagnosed with MMV. We further examined the risk of ischemic and hemorrhagic stroke in patients newly diagnosed with MMV without prior stroke. Hazard ratios (HR) were calculated using multivariable Cox regression models adjusted for relevant confounders.

Results

Over a media

SUBMITTER: Lee J 

PROVIDER: S-EPMC12684627 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature