Left Ventricular Mass-to-Strain Ratio to Predict Change in Left Ventricular Hypertrophy and Prognosis in Hypertensive Heart Disease.

ABSTRACT:

Background

A typical hypertensive heart disease phenotype is the left ventricular hypertrophy (LVH) and dysfunction, measurable via LV mass and global longitudinal strain. We aimed to evaluate the LV mass-to-strain ratio (LV-MSR) as a marker of the clinical course in patients with hypertensive heart disease.

Methods

We retrospectively analyzed consecutive patients who underwent echocardiography at the time of hypertension diagnosis and at 6- to 18-month intervals in tertiary centers from 2006 to 2021. Associations of LV-MSR with LVH changes and clinical outcomes (cardiovascular death and heart failure hospitalization occurring after the second echocardiogram) were assessed using time-dependent receiver-operating characteristic analysis and multivariable Cox regression.

Re

SUBMITTER: Hwang IC 

PROVIDER: S-EPMC12684636 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature