Target and biomarker exploration portal for drug discovery.

ABSTRACT:

Motivation

The discovery of novel drug targets and precision biomarkers remains a major challenge in drug development, with traditional differential expression analysis often overlooking key regulatory proteins. Here, we present a novel, web-based bioinformatics tool, the Target and Biomarker Exploration Portal (TBEP), designed to accelerate the drug discovery process by integrating large-scale biomedical data with network analysis techniques.

Results

TBEP harnesses machine-learning approaches to mine and combine multimodal datasets, including human genetics, functional genomics, and protein-protein interaction networks, to decode causal disease mechanisms and uncover novel therapeutic targets and precision biomarkers for specific phenotypes. A unique feature of the tool is

SUBMITTER: Dewangan B 

PROVIDER: S-EPMC12684723 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature