Blood Pressure Variability and Adverse Pregnancy and Cardiovascular Outcomes in the ALSPAC Cohort.

ABSTRACT:

Background

Outside pregnancy, blood pressure variability (BPV) predicts cardiovascular events. We aimed to study associations (if any) between visit-to-visit BPV in pregnancy and (1) adverse maternal/perinatal outcomes, and (2) long-term maternal cardiovascular outcomes. We conducted a secondary analysis of data from ALSPAC (Avon Longitudinal Study of Parents and Children).

Methods

Adjusted logistic regression assessed relationships between visit-to-visit BPV (by the measures of SD, average real variability, and variability independent of mean) and pregnancy outcomes (gestational/severe hypertension, preeclampsia, preterm birth, small-for-gestational-age infants, neonatal intensive care unit admission, stillbirth, and perinatal death). Adjusted Cox regression assessed relati

SUBMITTER: Wilson M 

PROVIDER: S-EPMC12684795 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature