Lipophagy acts as a nutritional adaptation mechanism for the filamentous entomopathogenic fungus Beauveria bassiana to colonize within the hosts.

ABSTRACT:

Introduction

Metabolic adaptation to various nutrients is crucial for the pathogenic growth and virulence of filamentous fungal pathogens. Despite its importance, the mechanisms underlying fungal adaptation to nutrient shifts, especially at the subcellular level, remain incompletely understood.

Objectives

Our study aims to investigate the mechanisms involved in metabolic adaptation in filamentous fungi.

Methods

The filamentous entomopathogenic fungus Beauveria bassiana was used as a representative of filamentous fungi. Gene functional analyses were conducted via gene disruption and complementation. Vacuolar targeting of lipid droplets were determined with transmission electron microscopy and fluorescence microscopy. Protein interaction was determined with yeast-two hy

SUBMITTER: Ding JL 

PROVIDER: S-EPMC12684906 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature