Multiplex Magnetic Biosensor Microarrays Facilitate Personalized Vaccination Schedules for SARS-CoV-2 Variants.

ABSTRACT: Rapid, sensitive, multiplexed antibody detection technologies are essential for assessing vaccine efficacy and recipient immunity against viruses. As severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants continue to emerge and novel viruses may pose potential threats in the near future, personalized vaccines can be precisely tailored to an individual's measured immunity to help mitigate the symptoms of infection and viral spread. Here, we present giant magnetoresistive (GMR) biosensor microarrays for the quantitative multiplexed detection of antibodies against SARS-CoV-2 variants. The multiplexed GMR biosensor microarrays demonstrated high sensitivity, comparable to that of the single-plex enzyme-linked immunosorbent assay, enabling multiplexed measurements using blood obta

SUBMITTER: Um HK 

PROVIDER: S-EPMC12685006 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature