Chromosomal deletions in banana somaclonal variants reveal negative regulators of immunity underlying <i>Fusarium</i> wilt resistance.

ABSTRACT: Fusarium wilt, caused by Fusarium oxysporum f. sp. cubense tropical race 4 (TR4), poses a severe threat to global banana production. Developing TR4-resistant banana cultivars has been challenging due to triploidy and sterility. Nevertheless, several Cavendish somaclonal variants with stable TR4 resistance have been developed and widely cultivated in Taiwan. Despite this success, the underlying genetic and molecular bases remain largely unknown, limiting the broader application of this resistance to other varieties. Here, we apply genomic and functional analyses to uncover somatic mutations and key genes associated with TR4 resistance. We observe recurrent selection for large deletions on chromosome 5 and a tendency for elevated expression of salicylic acid-responsive g

SUBMITTER: Singh PT 

PROVIDER: S-EPMC12685060 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature