Time-varying comparative effectiveness of surgical or percutaneous revascularization on patient-centred outcomes.

ABSTRACT:

Background

Little is known about the comparative risks and timing of patient-defined adverse cardiovascular and noncardiovascular events (PACE) after coronary artery revascularization. We investigated comparative risks of PACEs after coronary artery bypass grafting (CABG) or percutaneous coronary intervention (PCI).

Methods

We conducted a retrospective cohort study of patients who underwent isolated index myocardial revascularization procedures between Oct. 1, 2008, and Dec. 31, 2018, in Ontario, Canada. The primary exposure was revascularization by CABG or PCI. The primary outcome was PACE, a composite of postoperative severe stroke, ventilator dependence, new-onset or worsening heart failure, long-term care admission, and new-onset dialysis. We modelled the association of

SUBMITTER: Fielding-Singh V 

PROVIDER: S-EPMC12685096 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature