SUPPRESSOR OF LAZY QUADRUPLE 1 acts at ER-plasma membrane contact sites to control a gravitropism pathway in the <i>Arabidopsis</i> stem.

ABSTRACT: LAZY proteins function early in the process of orienting growth of land plants with respect to the gravity vector (gravitropism). In Arabidopsis, an oppositely oriented and LAZY-independent form of gravitropism causes the inflorescence stems of a lazy quadruple mutant (atlazy1;2;3;4) to grow down and along the surface of the soil. Here, we report on a suppressor mutation that restores an upright inflorescence to a plant lacking LAZY functions. The suppressor of lazy quadruple 1 (slq1) mutation alters one amino acid in a protein belonging to the NPH3/RPT2-like (NRL) family. The wild-type SLQ1 protein restores prostrate growth to the atlazy1;2;3;4 mutant when expressed specifically in the gravity-sensing endo

SUBMITTER: Yoshihara T 

PROVIDER: S-EPMC12685104 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature