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Blood draw site and blood matrix influence mineral assessment.


ABSTRACT: Circulating mineral concentrations are used to assess nutritional status or as markers for clinical conditions, but the quality of these measurements depends on the methods used for blood processing. Since the procedures for measuring mineral levels in blood are not standardized, discrepancies in sampling may influence the analytical results. We previously reported that zinc content in blood samples showed significant variation depending on several pre-analytical variables selected during blood collection and processing. In this study, we extend our analysis to determine how other mineral levels might be affected by different blood draw sites (capillary or venous) or sample matrices (plasma or serum). Sequential capillary and venous blood samples were collected from a diverse cohort of six

SUBMITTER: Alejandro MG 

PROVIDER: S-EPMC12685167 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature