Dosing trajectories of antihypertensive agents among preterm neonates: A retrospective, cross-sectional analysis.

ABSTRACT:

Introduction

Preterm infants are at increased risk for hypertension due to incomplete organ development. With no established guidelines for treating hypertension in this population, clinicians rely on their experience, and little is known regarding those treatment decisions. This study described dosing trajectories for the three most common antihypertensive agents in preterm infants.

Methods

This retrospective, cross-sectional study examined preterm neonates (gestational age at birth < 37 weeks, postmenstrual age < 44 weeks) treated with antihypertensive medications at the University of Alabama at Birmingham (UAB) Medical Center. The study identified the three most common antihypertensive agents and identified common dosing patterns over time using the functional K-means alg

SUBMITTER: Pittman MC 

PROVIDER: S-EPMC12685197 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature