NIRS frequency analysis to evaluate cerebrovascular reactivity after acute brain injury.

ABSTRACT:

Significance

Cerebral autoregulation (CA) relies on cerebrovascular reactivity, and it is often impaired after acute brain injury (ABI), contributing to secondary brain damage. Noninvasive neuromonitoring with near-infrared spectroscopy (NIRS) can detect oscillations in cerebral hemodynamics, which may reflect autoregulatory function and may therefore be a candidate biomarker for CA monitoring.

Aim

We investigated whether changes in the spectral composition of the NIRS signal in ABI under the condition of mild hyperoxia are associated with clinical outcomes in ABI patients.

Approach

Bilateral prefrontal NIRS recording was performed during hyperoxia challenges in mechanically ventilated ABI patients admitted to the neurocritical care unit. Spectral power in low-frequen

SUBMITTER: Bicciato G 

PROVIDER: S-EPMC12685250 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature