Intravascular Large B-Cell Lymphoma Presenting as Migraine with Aura: A Case Report.

ABSTRACT:

Introduction

Intravascular large B-cell lymphoma is a rare, fatal, aggressive lymphoma that is characterized by the proliferation of clonal lymphocytes within the lumen of small, medium, and large vessels. Diagnosis is challenging given the nonspecific initial presentation. Incidence is <1 case per 1 million per year worldwide.

Case report

We report a case of intravascular large B-cell lymphoma in a 62-year-old female who presented to the clinic with symptoms of migraine with aura. MRI brain showed T2 hyperintensities in the splenium of the corpus callosum, right frontal, and bilateral parietal lobes, which progressed on repeat imaging. Laboratory studies only showed mild elevation of alanine aminotransferase to 75 (8-35 U/L). Computed tomography of the chest, abdomen, and p

SUBMITTER: Moseley S 

PROVIDER: S-EPMC12685339 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature